Anti-TPRKB antibody [R06-7T-7] (STJA0033143)

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STJA0033143
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Short Description :Mouse monoclonal anti-TPRKB for use in WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ICC/IF
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :R06-7T-7
Isotype:IgG1k
Conjugation:Unconjugated
Purification:Protein A
Dilution Range:WB 1:1000-1:4000
ICC:IF 1:50
Formulation:Liquid in PBS, Glycerol and BSA
Storage Instruction:Store at-20°C. Avoid freeze/thaw cycles.
Gene Symbol:TPRKB
Gene ID:51002
Uniprot ID:TPRKB_HUMAN
Immunogen:Peptide
Tissue Specificity Widely expressed.
Function Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification.
Protein Name Ekc/Keops Complex Subunit Tprkb
Prpk-Binding Protein
Tp53rk-Binding Protein
Database Links Reactome: R-HSA-6782315
Cellular Localisation Cytoplasm
Cytosol
Nucleus
Alternative Antibody Names Anti-Ekc/Keops Complex Subunit Tprkb antibody
Anti-Prpk-Binding Protein antibody
Anti-Tp53rk-Binding Protein antibody
Anti-TPRKB antibody
Anti-CGI-121 antibody
Anti-My019 antibody

Information sourced from Uniprot.org

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