Anti-TPRKB antibody [R06-7T-7] (STJA0033143)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenPeptide
General Information
| Short Description | Mouse monoclonal anti-TPRKB for use in WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-7T-7 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Purification | Protein A |
| Dilution Range | WB 1:1000-1:4000ICC:IF 1:50 |
| Formulation | Liquid in PBS, Glycerol and BSA |
| Storage Instruction | Store at-20°C. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TPRKB |
| Gene ID | 51002 |
| Uniprot ID | TPRKB_HUMAN |
| Immunogen | Peptide |
Additional Info
| Tissue Specificity | Widely expressed. |
| Function | Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification. |
| Protein Name | Ekc/Keops Complex Subunit TprkbPrpk-Binding ProteinTp53rk-Binding Protein |
| Database Links | Reactome: R-HSA-6782315 |
| Cellular Localisation | CytoplasmCytosolNucleus |
| Alternative Antibody Names | Anti-Ekc/Keops Complex Subunit Tprkb antibodyAnti-Prpk-Binding Protein antibodyAnti-Tp53rk-Binding Protein antibodyAnti-TPRKB antibodyAnti-CGI-121 antibodyAnti-My019 antibody |
Information sourced from Uniprot.org