• Western blot analysis of lysates from HT-29 cells, treated with serum 20% 15', using TOB1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using TOB1 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-TOB1 antibody (130-179 aa) (STJ96058)

SKU:
STJ96058

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Protein Tob1 (130-179 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TOB1
Gene ID: 10140
Uniprot ID: TOB1_HUMAN
Immunogen Region: 130-179 aa
Specificity: TOB1 Polyclonal Antibody detects endogenous levels of TOB1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human TOB1 at the amino acid range 130-179
Post Translational Modifications Phosphorylated on Ser and Thr residues.
Function Anti-proliferative protein.the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Mediates CPEB3-accelerated mRNA deadenylation by binding to CPEB3 and recruiting CNOT7 which leads to target mRNA deadenylation and decay.
Protein Name Protein Tob1
Transducer Of Erbb-2 1
Cellular Localisation Cytoplasm
Nucleus
Only A Small Fraction Localizes To The Cytoplasm Except In Late S-Phase Where More Than Half Of Proteins Become Cytoplasmic
Alternative Antibody Names Anti-Protein Tob1 antibody
Anti-Transducer Of Erbb-2 1 antibody
Anti-TOB1 antibody
Anti-TOB antibody
Anti-TROB1 antibody

Information sourced from Uniprot.org

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