Anti-TOB1 antibody (130-179 aa) (STJ96058)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human TOB1 at the amino acid range 130-179
General Information
| Short Description | Rabbit polyclonal anti-Protein Tob1 (130-179 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TOB1 |
| Gene ID | 10140 |
| Uniprot ID | TOB1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human TOB1 at the amino acid range 130-179 |
| Immunogen Region | 130-179 aa |
| Specificity | TOB1 Polyclonal Antibody detects endogenous levels of TOB1 protein. |
Additional Info
| Post Translational Modifications | Phosphorylated on Ser and Thr residues. |
| Function | Anti-proliferative protein.the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Mediates CPEB3-accelerated mRNA deadenylation by binding to CPEB3 and recruiting CNOT7 which leads to target mRNA deadenylation and decay. |
| Protein Name | Protein Tob1Transducer Of Erbb-2 1 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusOnly A Small Fraction Localizes To The Cytoplasm Except In Late S-Phase Where More Than Half Of Proteins Become Cytoplasmic |
| Alternative Antibody Names | Anti-Protein Tob1 antibodyAnti-Transducer Of Erbb-2 1 antibodyAnti-TOB1 antibodyAnti-TOB antibodyAnti-TROB1 antibody |
Information sourced from Uniprot.org