Anti-TMED1 antibody (STJ192036)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Transmembrane emp24 domain-containing protein 1 for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TMED1 |
| Gene ID | 11018 |
| Uniprot ID | TMED1_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | TMED1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Potential role in vesicular protein trafficking, mainly in the early secretory pathway. May act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side. Plays a positive role in IL-33-mediated IL-8 and IL-6 production by interacting with interleukin-33 receptor IL1RL1. Also plays a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26. |
| Protein Name | Transmembrane Emp24 Domain-Containing Protein 1Interleukin-1 Receptor-Like 1 LigandPutative T1/St2 Receptor-Binding ProteinP24 Family Protein Gamma-1Tp24P24gamma1 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinEndoplasmic Reticulum MembraneGolgi ApparatusCis-Golgi Network MembraneEndoplasmic Reticulum-Golgi Intermediate Compartment Membrane |
| Alternative Antibody Names | Anti-Transmembrane Emp24 Domain-Containing Protein 1 antibodyAnti-Interleukin-1 Receptor-Like 1 Ligand antibodyAnti-Putative T1/St2 Receptor-Binding Protein antibodyAnti-P24 Family Protein Gamma-1 antibodyAnti-Tp24 antibodyAnti-P24gamma1 antibodyAnti-TMED1 antibodyAnti-IL1RL1L antibodyAnti-IL1RL1LG antibody |
Information sourced from Uniprot.org