• Western blot analysis of the lysates from HeLa cells using TINF2 antibody.
  • Western blot analysis of lysates from HUVEC cells, using TINF2 Antibody. The lane on the right is blocked with the synthesized peptide.

Anti-TINF2 antibody (71-120 aa) (STJ96027)

SKU:
STJ96027

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TERF1-interacting nuclear factor 2 (71-120 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TINF2
Gene ID: 26277
Uniprot ID: TINF2_HUMAN
Immunogen Region: 71-120 aa
Specificity: TIN2 Polyclonal Antibody detects endogenous levels of TIN2 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human TINF2 at the amino acid range 71-120
Function Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends.without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.
Protein Name Terf1-Interacting Nuclear Factor 2
Trf1-Interacting Nuclear Protein 2
Database Links Reactome: R-HSA-110328
Reactome: R-HSA-110329
Reactome: R-HSA-110330
Reactome: R-HSA-110331
Reactome: R-HSA-1221632
Reactome: R-HSA-171306
Reactome: R-HSA-171319
Reactome: R-HSA-174411
Reactome: R-HSA-174414
Reactome: R-HSA-174417
Reactome: R-HSA-174430
Reactome: R-HSA-174437
Reactome: R-HSA-2559586
Reactome: R-HSA-9670095
Cellular Localisation Nucleus
Chromosome
Telomere
Associated With Telomeres
Isoform 1: Nucleus Matrix
Alternative Antibody Names Anti-Terf1-Interacting Nuclear Factor 2 antibody
Anti-Trf1-Interacting Nuclear Protein 2 antibody
Anti-TINF2 antibody
Anti-TIN2 antibody

Information sourced from Uniprot.org

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