| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TIMP4 |
| Gene ID: | 7079 |
| Uniprot ID: | TIMP4_HUMAN |
| Immunogen Region: | 30-224 |
| Immunogen Sequence: | CSCAPAHPQQHICHSALVIR AKISSEKVVPASADPADTEK MLRYEIKQIKMFKGFEKVKD VQYIYTPFDSSLCGVKLEAN SQKQYLLTGQVLSDGKVFIH LCNYIEPWEDLSLVQRESLN HHYHLNCGCQITTCYTVPCT ISAPNECLWTDWLLERKLYG YQAQHYVCMKHVDGTCSWYR GHLPLRKEFVDIVQP |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-224 of human TIMP4 (NP_003247.1). |
| Tissue Specificity | Abundant in heart and present at low levels in many other tissues. |
| Function | Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9. |
| Protein Name | Metalloproteinase Inhibitor 4Tissue Inhibitor Of Metalloproteinases 4Timp-4 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Metalloproteinase Inhibitor 4 antibodyAnti-Tissue Inhibitor Of Metalloproteinases 4 antibodyAnti-Timp-4 antibodyAnti-TIMP4 antibody |
Information sourced from Uniprot.org
