Anti-TIMP4 antibody (30-224) (STJ28499)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TIMP4 (30-224) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TIMP4 |
| Gene ID | 7079 |
| Uniprot ID | TIMP4_HUMAN |
| Immunogen Region | 30-224 |
| Immunogen Sequence | CSCAPAHPQQHICHSALVIR AKISSEKVVPASADPADTEK MLRYEIKQIKMFKGFEKVKD VQYIYTPFDSSLCGVKLEAN SQKQYLLTGQVLSDGKVFIH LCNYIEPWEDLSLVQRESLN HHYHLNCGCQITTCYTVPCT ISAPNECLWTDWLLERKLYG YQAQHYVCMKHVDGTCSWYR GHLPLRKEFVDIVQP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 30-224 of human TIMP4 (NP_003247.1). |
Additional Info
| Tissue Specificity | Abundant in heart and present at low levels in many other tissues. |
| Function | Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9. |
| Protein Name | Metalloproteinase Inhibitor 4Tissue Inhibitor Of Metalloproteinases 4Timp-4 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Metalloproteinase Inhibitor 4 antibodyAnti-Tissue Inhibitor Of Metalloproteinases 4 antibodyAnti-Timp-4 antibodyAnti-TIMP4 antibody |
Information sourced from Uniprot.org