Anti-TIMM22 antibody (20-120) [S5150RM] (STJ11105150)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Mitochondrial Import Inner Membrane Translocase Subunit Tim22 (20-120) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S5150RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TIMM22 |
| Gene ID | 29928 |
| Uniprot ID | TIM22_HUMAN |
| Immunogen Region | 20-120 |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 20-120aa of human TIMM22. |
Additional Info
| Post Translational Modifications | Disulfide bonds promote efficient assembly of the TIM22 complex. |
| Function | Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps. |
| Protein Name | Mitochondrial Import Inner Membrane Translocase Subunit Tim22Testis-Expressed Protein 4 |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim22 antibodyAnti-Testis-Expressed Protein 4 antibodyAnti-TIMM22 antibodyAnti-TEX4 antibodyAnti-TIM22 antibody |
Information sourced from Uniprot.org