Anti-Thyroid Peroxidase antibody [AC25] (STJ16101796)

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STJ16101796-1
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Short Description :Mouse monoclonal anti-Thyroid Peroxidase for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-P
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :AC25
Isotype:IgG1
Conjugation:Unconjugated
Concentration:>=10.8 mg/L
Dilution Range:IHC-P 1:80
Formulation:Tissue culture supernatant with sodium azide
Storage Instruction:Store at 2-8°C for up to 1-year, upon receipt.
Gene Symbol:TPO
Gene ID:7173
Uniprot ID:PERT_HUMAN
Immunogen:Prokaryotic recombinant protein containing 105 amino acids corresponding to a portion of the N-terminus of the human thyroid peroxidase molecule.
Post Translational Modifications Glycosylated. Heme is covalently bound through a H(2)O(2)-dependent autocatalytic process. Heme insertion is important for the delivery of protein at the cell surface. Cleaved in its N-terminal part.
Function Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4).
Protein Name Thyroid Peroxidase
Tpo
Database Links Reactome: R-HSA-209968
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Isoform 3: Cell Surface
Alternative Antibody Names Anti-Thyroid Peroxidase antibody
Anti-Tpo antibody
Anti-TPO antibody

Information sourced from Uniprot.org