| Host: |
Mouse |
| Applications: |
IHC-P |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Thyroid Peroxidase is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
AC25 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1 |
| Formulation: |
Tissue culture supernatant with sodium azide |
| Concentration: |
>=10.8 mg/L |
| Dilution Range: |
IHC-P 1:80 |
| Storage Instruction: |
Store at 2-8°C upon receipt. |
| Gene Symbol: |
TPO |
| Gene ID: |
7173 |
| Uniprot ID: |
PERT_HUMAN |
| Immunogen: |
Prokaryotic recombinant protein containing 105 amino acids corresponding to a portion of the N-terminus of the human thyroid peroxidase molecule. |
| Post Translational Modifications | Glycosylated. Heme is covalently bound through a H(2)O(2)-dependent autocatalytic process. Heme insertion is important for the delivery of protein at the cell surface. Cleaved in its N-terminal part. |
| Function | Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4). |
| Protein Name | Thyroid PeroxidaseTpo |
| Database Links | Reactome: R-HSA-209968 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinIsoform 3: Cell Surface |
| Alternative Antibody Names | Anti-Thyroid Peroxidase antibodyAnti-Tpo antibodyAnti-TPO antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
