Anti-TFR2 antibody (130-330) (STJ111887)

Name: Anti-TFR2 antibody (130-330) (STJ111887)
SKU: STJ111887
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ111887

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Short Description	Rabbit polyclonal TFR2 (130-330) antibody for use in WB, IHC-P, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 IHC-P:1:50-1:200 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	TFR2
Gene ID	7036
Uniprot ID	TFR2_HUMAN
Immunogen Region	130-330
Immunogen Sequence	FHQGRLYWSDLQAMFLQFLG EGRLEDTIRQTSLRERVAGS AGMAALTQDIRAALSRQKLD HVWTDTHYVGLQFPDPAHPN TLHWVDEAGKVGEQLPLEDP DVYCPYSAIGNVTGELVYAH YGRPEDLQDLRARGVDPVGR LLLVRVGVISFAQKVTNAQD FGAQGVLIYPEPADFSQDPP KPSLSSQQAVYGHVHLGTGD P
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 130-330 of human TFR2 (NP_003218.2).

Tissue Specificity	Predominantly expressed in liver. While the alpha form is also expressed in spleen, lung, muscle, prostate and peripheral blood mononuclear cells, the beta form is expressed in all tissues tested, albeit weakly.
Function	Mediates cellular uptake of transferrin-bound iron in a non-iron dependent manner. May be involved in iron metabolism, hepatocyte function and erythrocyte differentiation.
Protein Name	Transferrin Receptor Protein 2 Tfr2
Database Links	Reactome: R-HSA-917977
Cellular Localisation	Cell Membrane Single-Pass Type Ii Membrane Protein Isoform Beta: Cytoplasm Lacks The Transmembrane Domain Probably Intracellular
Alternative Antibody Names	Anti-Transferrin Receptor Protein 2 antibody Anti-Tfr2 antibody Anti-TFR2 antibody

Information sourced from Uniprot.org