Anti-TFCP2 antibody (1-280) (STJ27501)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ27501
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General Information

Short DescriptionRabbit polyclonal TFCP2 (1-280) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolTFCP2
Gene ID7024
Uniprot IDTFCP2_HUMAN
Immunogen Region1-280
Immunogen SequenceMAWALKLPLADEVIESGLVQ DFDASLSGIGQELGAGAYSM SDVLALPIFKQEESSLPPDN ENKILPFQYVLCAATSPAVK LHDETLTYLNQGQSYEIRML DNRKLGELPEINGKLVKSIF RVVFHDRRLQYTEHQQLEGW RWNRPGDRILDIDIPMSVGI IDPRANPTQLNTVEFLWDPA KRTSVFIQVHCISTEFTMRK HGGEKGVPFRVQIDTFKENE NGEYTEHLHSASCQIKVFK
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TFCP2 (NP_005644.2).

Additional Info

Tissue Specificity Ubiquitous. Expressed in brain, ovary, kidney, thymus, spleen, liver, adrenal, heart and lung (at protein level).
Function Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1. Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter.
Protein Name Alpha-Globin Transcription Factor Cp2
Saa3 Enhancer Factor
Transcription Factor Lsf
Database Links
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Alpha-Globin Transcription Factor Cp2 antibody
Anti-Saa3 Enhancer Factor antibody
Anti-Transcription Factor Lsf antibody
Anti-TFCP2 antibody
Anti-LSF antibody
Anti-SEF antibody

Information sourced from Uniprot.org

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