| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TFCP2 |
| Gene ID: | 7024 |
| Uniprot ID: | TFCP2_HUMAN |
| Immunogen Region: | 1-280 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TFCP2 (NP_005644.2). |
| Immunogen Sequence: | MAWALKLPLADEVIESGLVQ DFDASLSGIGQELGAGAYSM SDVLALPIFKQEESSLPPDN ENKILPFQYVLCAATSPAVK LHDETLTYLNQGQSYEIRML DNRKLGELPEINGKLVKSIF RVVFHDRRLQYTEHQQLEGW RWNRPGDRILDIDIPMSVGI IDPRANPTQLNTVEFLWDPA KRTSVFIQVHCISTEFTMRK HGGEKGVPFRVQIDTFKENE NGEYTEHLHSASCQIKVFK |
| Tissue Specificity | Ubiquitous. Expressed in brain, ovary, kidney, thymus, spleen, liver, adrenal, heart and lung (at protein level). |
| Function | Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1. Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter. |
| Protein Name | Alpha-Globin Transcription Factor Cp2 Saa3 Enhancer Factor Transcription Factor Lsf |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Alpha-Globin Transcription Factor Cp2 antibody Anti-Saa3 Enhancer Factor antibody Anti-Transcription Factor Lsf antibody Anti-TFCP2 antibody Anti-LSF antibody Anti-SEF antibody |
Information sourced from Uniprot.org
