Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | TFCP2 |
Gene ID: | 7024 |
Uniprot ID: | TFCP2_HUMAN |
Immunogen Region: | 1-280 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TFCP2 (NP_005644.2). |
Immunogen Sequence: | MAWALKLPLADEVIESGLVQ DFDASLSGIGQELGAGAYSM SDVLALPIFKQEESSLPPDN ENKILPFQYVLCAATSPAVK LHDETLTYLNQGQSYEIRML DNRKLGELPEINGKLVKSIF RVVFHDRRLQYTEHQQLEGW RWNRPGDRILDIDIPMSVGI IDPRANPTQLNTVEFLWDPA KRTSVFIQVHCISTEFTMRK HGGEKGVPFRVQIDTFKENE NGEYTEHLHSASCQIKVFK |
Tissue Specificity | Ubiquitous. Expressed in brain, ovary, kidney, thymus, spleen, liver, adrenal, heart and lung (at protein level). |
Function | Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1. Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter. |
Protein Name | Alpha-Globin Transcription Factor Cp2 Saa3 Enhancer Factor Transcription Factor Lsf |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Alpha-Globin Transcription Factor Cp2 antibody Anti-Saa3 Enhancer Factor antibody Anti-Transcription Factor Lsf antibody Anti-TFCP2 antibody Anti-LSF antibody Anti-SEF antibody |
Information sourced from Uniprot.org