• Western blot analysis of various lysates using TCN1 Rabbit polyclonal antibody (STJ28497) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-TCN1 antibody (24-280) (STJ28497)

SKU:
STJ28497

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TCN1 (24-280) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TCN1
Gene ID: 6947
Uniprot ID: TCO1_HUMAN
Immunogen Region: 24-280
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-280 of human TCN1 (NP_001053.2).
Immunogen Sequence: EICEVSEENYIRLKPLLNTM IQSNYNRGTSAVNVVLSLKL VGIQIQTLMQKMIQQIKYNV KSRLSDVSSGELALIILALG VCRNAEENLIYDYHLIDKLE NKFQAEIENMEAHNGTPLTN YYQLSLDVLALCLFNGNYST AEVVNHFTPENKNYYFGSQF SVDTGAMAVLALTCVKKSLI NGQIKADEGSLKNISIYTKS LVEKILSEKKENGLIGNTFS TGEAMQALFVSSDYYNEND
Tissue Specificity Produced by the salivary glands of the oral cavity, in response to ingestion of food. Major constituent of secondary granules in neutrophils.
Post Translational Modifications Contains about 30% carbohydrates.
Function Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.
Protein Name Transcobalamin-1
Tc-1
Haptocorrin
Hc
Protein R
Transcobalamin I
Tc I
Tci
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-9758881
Reactome: R-HSA-9758890
Cellular Localisation Secreted
Alternative Antibody Names Anti-Transcobalamin-1 antibody
Anti-Tc-1 antibody
Anti-Haptocorrin antibody
Anti-Hc antibody
Anti-Protein R antibody
Anti-Transcobalamin I antibody
Anti-Tc I antibody
Anti-Tci antibody
Anti-TCN1 antibody
Anti-TC1 antibody

Information sourced from Uniprot.org

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