Anti-TCF25 antibody (STJ191531)

SKU:
STJ191531
€60.00 - €315.00
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Ribosome quality control complex subunit TCF25 is suitable for use in Western Blot and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TCF25
Gene ID: 22980
Uniprot ID: TCF25_HUMAN
Specificity: TCF25 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from part of the human protein
Function Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. In the RQC complex, required to promote formation of 'Lys-48'-linked polyubiquitin chains during ubiquitination of incompletely synthesized proteins by LTN1. May negatively regulate the calcineurin-NFAT signaling cascade by suppressing the activity of transcription factor NFATC4. May play a role in cell death control.
Protein Name Ribosome Quality Control Complex Subunit Tcf25
Nuclear Localized Protein 1
Transcription Factor 25
Tcf-25
Database Links
Cellular Localisation Nucleus
Cytoplasm
Cytosol
Mainly Nuclear
Alternative Antibody Names Anti-Ribosome Quality Control Complex Subunit Tcf25 antibody
Anti-Nuclear Localized Protein 1 antibody
Anti-Transcription Factor 25 antibody
Anti-Tcf-25 antibody
Anti-TCF25 antibody
Anti-KIAA1049 antibody
Anti-NULP1 antibody
Anti-FKSG26 antibody

Information sourced from Uniprot.org

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