| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Ribosome quality control complex subunit TCF25 is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TCF25 |
| Gene ID: |
22980 |
| Uniprot ID: |
TCF25_HUMAN |
| Specificity: |
TCF25 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from part of the human protein |
| Function | Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. In the RQC complex, required to promote formation of 'Lys-48'-linked polyubiquitin chains during ubiquitination of incompletely synthesized proteins by LTN1. Also acts as a transcriptional repressor: represses transcription of SRF in vitro and so may play a role in heart development. May play a role in cell death control. |
| Protein Name | Ribosome Quality Control Complex Subunit Tcf25Nuclear Localized Protein 1Transcription Factor 25Tcf-25 |
| Cellular Localisation | NucleusCytoplasmCytosolMainly Nuclear |
| Alternative Antibody Names | Anti-Ribosome Quality Control Complex Subunit Tcf25 antibodyAnti-Nuclear Localized Protein 1 antibodyAnti-Transcription Factor 25 antibodyAnti-Tcf-25 antibodyAnti-TCF25 antibodyAnti-KIAA1049 antibodyAnti-NULP1 antibodyAnti-FKSG26 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
