| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TBX5 (1-70) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TBX5 |
| Gene ID: |
6910 |
| Uniprot ID: |
TBX5_HUMAN |
| Immunogen Region: |
1-70 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human TBX5 (NP_852259.1). |
| Immunogen Sequence: |
MADADEGFGLAHTPLEPDAK DLPCDSKPESALGAPSKSPS SPQAAFTQQGMEGIKVFLHE RELWLKFHEV |
| Post Translational Modifications | Acetylation at Lys-339 by KAT2A and KAT2B promotes nuclear retention. |
| Function | DNA-binding protein that regulates the transcription of several genes and is involved in heart development and limb pattern formation. Binds to the core DNA motif of NPPA promoter. |
| Protein Name | T-Box Transcription Factor Tbx5T-Box Protein 5 |
| Database Links | Reactome: R-HSA-2032785Reactome: R-HSA-5578768Reactome: R-HSA-9733709 |
| Cellular Localisation | NucleusCytoplasmShuttles Between The Cytoplasm And The NucleusAcetylation At Lys-339 Promotes Nuclear Retention |
| Alternative Antibody Names | Anti-T-Box Transcription Factor Tbx5 antibodyAnti-T-Box Protein 5 antibodyAnti-TBX5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
