• Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-TBCB antibody (STJ191559)

SKU:
STJ191559

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Tubulin-folding cofactor B is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TBCB
Gene ID: 1155
Uniprot ID: TBCB_HUMAN
Specificity: TBCB Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from part of the human protein
Post Translational Modifications Phosphorylation by PAK1 is required for normal function. Ubiquitinated in the presence of GAN which targets it for degradation by the proteasome. (Microbial infection) Glycosylated residues by S.typhimurium protein Ssek1: arginine GlcNAcylation promotes microtubule stability.
Function Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.
Protein Name Tubulin-Folding Cofactor B
Cytoskeleton-Associated Protein 1
Cytoskeleton-Associated Protein Ckapi
Tubulin-Specific Chaperone B
Database Links Reactome: R-HSA-389977
Cellular Localisation Cytoplasm
Cytoskeleton
Colocalizes With Microtubules
In Differentiated Neurons
Located In The Cytoplasm
In Differentiating Neurons
Accumulates At The Growth Cone
Alternative Antibody Names Anti-Tubulin-Folding Cofactor B antibody
Anti-Cytoskeleton-Associated Protein 1 antibody
Anti-Cytoskeleton-Associated Protein Ckapi antibody
Anti-Tubulin-Specific Chaperone B antibody
Anti-TBCB antibody
Anti-CG22 antibody
Anti-CKAP1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance