Anti-TAS2R14 antibody (229-278 aa) (STJ95871)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human TAS2R14 at the amino acid range 229-278
General Information
| Short Description | Rabbit polyclonal anti-Taste receptor type 2 member 14 (229-278 aa) for use in WB and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TAS2R14 |
| Gene ID | 50840 |
| Uniprot ID | T2R14_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human TAS2R14 at the amino acid range 229-278 |
| Immunogen Region | 229-278 aa |
| Specificity | T2R14 Polyclonal Antibody detects endogenous levels of T2R14 protein. |
Additional Info
| Function | Gustducin-linked G-protein coupled receptor that plays a role in the perception of bitterness. The activity of this receptor stimulates GNAT3, activating the gustducin G-protein pathway. Likely plays a role in sensing the chemical composition of the gastrointestinal content and other extra-oral tissues via the inhibitory G-protein pathways. |
| Protein Name | Taste Receptor Type 2 Member 14T2r14Taste Receptor Family B Member 1Trb1 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-420499Reactome: R-HSA-9717207 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Taste Receptor Type 2 Member 14 antibodyAnti-T2r14 antibodyAnti-Taste Receptor Family B Member 1 antibodyAnti-Trb1 antibodyAnti-TAS2R14 antibody |
Information sourced from Uniprot.org