Western blot analysis of extracts of various cell lines, using Neurokinin 1 Receptor (NK1R) (NK1R) Rabbit monoclonal antibody (STJ11102127) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-TACR1 antibody (300-407) [S7MR] (STJ11102127)

⇓ Datasheet ⇓ SDS
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ11102127
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General Information

Short DescriptionRabbit monoclonal Neurokinin 1 Receptor (300-407) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDS7MR
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolTACR1
Gene ID6869
Uniprot IDNK1R_HUMAN
Immunogen Region300-407
Immunogen SequenceYNPIIYCCLNDRFRLGFKHA FRCCPFISAGDYEGLEMKST RYLQTQGSVYKVSRLETTIS TVVGAHEEEPEDGPKATPSS LDLTSNCSSRSDSKTMTESF SFSSNVLS
SpecificityA synthetic peptide corresponding to a sequence within amino acids 300-407 of human Neurokinin 1 Receptor (NK1R) (NK1R) (P25103).

Additional Info

Function This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
Protein Name Substance-P Receptor
Spr
Nk-1 Receptor
Nk-1r
Tachykinin Receptor 1
Database Links Reactome: R-HSA-380095
Reactome: R-HSA-416476
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Substance-P Receptor antibody
Anti-Spr antibody
Anti-Nk-1 Receptor antibody
Anti-Nk-1r antibody
Anti-Tachykinin Receptor 1 antibody
Anti-TACR1 antibody
Anti-NK1R antibody
Anti-TAC1R antibody

Information sourced from Uniprot.org

Citations

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