• Western blot analysis of extracts of various cell lines, using Neurokinin 1 Receptor (NK1R) (NK1R) Rabbit monoclonal antibody (STJ11102127) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-TACR1 antibody (300-407) [S7MR] (STJ11102127)

SKU:
STJ11102127

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Neurokinin 1 Receptor (300-407) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S7MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TACR1
Gene ID: 6869
Uniprot ID: NK1R_HUMAN
Immunogen Region: 300-407
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300-407 of human Neurokinin 1 Receptor (NK1R) (NK1R) (P25103).
Immunogen Sequence: YNPIIYCCLNDRFRLGFKHA FRCCPFISAGDYEGLEMKST RYLQTQGSVYKVSRLETTIS TVVGAHEEEPEDGPKATPSS LDLTSNCSSRSDSKTMTESF SFSSNVLS
Function This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
Protein Name Substance-P Receptor
Spr
Nk-1 Receptor
Nk-1r
Tachykinin Receptor 1
Database Links Reactome: R-HSA-380095
Reactome: R-HSA-416476
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Substance-P Receptor antibody
Anti-Spr antibody
Anti-Nk-1 Receptor antibody
Anti-Nk-1r antibody
Anti-Tachykinin Receptor 1 antibody
Anti-TACR1 antibody
Anti-NK1R antibody
Anti-TAC1R antibody

Information sourced from Uniprot.org