Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit monoclonal antibody anti-Neurokinin 1 Receptor (300-407) is suitable for use in Western Blot research applications. |
Clonality: | Monoclonal |
Clone ID: | S7MR |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | TACR1 |
Gene ID: | 6869 |
Uniprot ID: | NK1R_HUMAN |
Immunogen Region: | 300-407 |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300-407 of human Neurokinin 1 Receptor (NK1R) (NK1R) (P25103). |
Immunogen Sequence: | YNPIIYCCLNDRFRLGFKHA FRCCPFISAGDYEGLEMKST RYLQTQGSVYKVSRLETTIS TVVGAHEEEPEDGPKATPSS LDLTSNCSSRSDSKTMTESF SFSSNVLS |
Function | This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. |
Protein Name | Substance-P Receptor Spr Nk-1 Receptor Nk-1r Tachykinin Receptor 1 |
Database Links | Reactome: R-HSA-380095 Reactome: R-HSA-416476 Reactome: R-HSA-8856825 Reactome: R-HSA-8856828 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
Alternative Antibody Names | Anti-Substance-P Receptor antibody Anti-Spr antibody Anti-Nk-1 Receptor antibody Anti-Nk-1r antibody Anti-Tachykinin Receptor 1 antibody Anti-TACR1 antibody Anti-NK1R antibody Anti-TAC1R antibody |
Information sourced from Uniprot.org