• Western blot analysis of lysates from SW620 cells, using TAC1 Rabbit polyclonal antibody (STJ25766) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-TAC1 antibody (1-129) (STJ25766)

SKU:
STJ25766

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TAC1 (1-129) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TAC1
Gene ID: 6863
Uniprot ID: TKN1_HUMAN
Immunogen Region: 1-129
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-129 of human TAC1 (NP_003173.1).
Immunogen Sequence: MKILVALAVFFLVSTQLFAE EIGANDDLNYWSDWYDSDQI KEELPEPFEHLLQRIARRPK PQQFFGLMGKRDADSSIEKQ VALLKALYGHGQISHKRHKT DSFVGLMGKRALNSVAYERS AMQNYERRR
Post Translational Modifications Substance P: The substance P form is cleaved at Pro-59 by the prolyl endopeptidase FAP (seprase) activity (in vitro). Substance P is also cleaved and degraded by Angiotensin-converting enzyme (ACE) and neprilysin (MME).
Function Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
Protein Name Protachykinin-1
Ppt Cleaved Into - Substance P - Neurokinin A
Nka
Neuromedin L
Substance K - Neuropeptide K
Npk - Neuropeptide Gamma - C-Terminal-Flanking Peptide
Database Links Reactome: R-HSA-380095
Reactome: R-HSA-416476
Cellular Localisation Secreted
Alternative Antibody Names Anti-Protachykinin-1 antibody
Anti-Ppt Cleaved Into - Substance P - Neurokinin A antibody
Anti-Nka antibody
Anti-Neuromedin L antibody
Anti-Substance K - Neuropeptide K antibody
Anti-Npk - Neuropeptide Gamma - C-Terminal-Flanking Peptide antibody
Anti-TAC1 antibody
Anti-NKA antibody
Anti-NKNA antibody
Anti-TAC2 antibody

Information sourced from Uniprot.org

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