Anti-TAC1 antibody (1-129) (STJ25766)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TAC1 (1-129) antibody for use in WB, IF, ICC and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TAC1 |
| Gene ID | 6863 |
| Uniprot ID | TKN1_HUMAN |
| Immunogen Region | 1-129 |
| Immunogen Sequence | MKILVALAVFFLVSTQLFAE EIGANDDLNYWSDWYDSDQI KEELPEPFEHLLQRIARRPK PQQFFGLMGKRDADSSIEKQ VALLKALYGHGQISHKRHKT DSFVGLMGKRALNSVAYERS AMQNYERRR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-129 of human TAC1 (NP_003173.1). |
Additional Info
| Post Translational Modifications | Substance P: The substance P form is cleaved at Pro-59 by the prolyl endopeptidase FAP (seprase) activity (in vitro). Substance P is also cleaved and degraded by Angiotensin-converting enzyme (ACE) and neprilysin (MME). |
| Function | Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. |
| Protein Name | Protachykinin-1Ppt Cleaved Into - Substance P - Neurokinin ANkaNeuromedin LSubstance K - Neuropeptide KNpk - Neuropeptide Gamma - C-Terminal-Flanking Peptide |
| Database Links | Reactome: R-HSA-380095Reactome: R-HSA-416476 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Protachykinin-1 antibodyAnti-Ppt Cleaved Into - Substance P - Neurokinin A antibodyAnti-Nka antibodyAnti-Neuromedin L antibodyAnti-Substance K - Neuropeptide K antibodyAnti-Npk - Neuropeptide Gamma - C-Terminal-Flanking Peptide antibodyAnti-TAC1 antibodyAnti-NKA antibodyAnti-NKNA antibodyAnti-TAC2 antibody |
Information sourced from Uniprot.org