Anti-SYT1 antibody (1-100) (STJ11105483)

Name: Anti-SYT1 antibody (1-100) (STJ11105483)
SKU: STJ11105483
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11105483

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Short Description	Rabbit polyclonal Synaptotagmin-1 (1-100) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:1000-1:5000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	SYT1
Gene ID	6857
Uniprot ID	SYT1_HUMAN
Immunogen Region	1-100
Immunogen Sequence	MVSESHHEALAAPPVTTVAT VLPSNATEPASPGEGKEDAF SKLKEKFMNELHKIPLPPWA LIAIAIVAVLLVLTCCFCIC KKCLFKKKNKKKGKEKGGKN
Specificity	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SYT1 (NP_005630.1).

Tissue Specificity	Expressed in melanocytes.
Post Translational Modifications	Glycosylated.
Function	Calcium sensor that participates in triggering neurotransmitter release at the synapse. May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner.these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes.
Protein Name	Synaptotagmin-1 Synaptotagmin I Syti P65
Database Links	Reactome: R-HSA-181429 Reactome: R-HSA-181430 Reactome: R-HSA-210500 Reactome: R-HSA-212676 Reactome: R-HSA-264642 Reactome: R-HSA-5250958 Reactome: R-HSA-5250989 Reactome: R-HSA-6794361 Reactome: R-HSA-8856825 Reactome: R-HSA-8856828 Reactome: R-HSA-888590
Cellular Localisation	Cytoplasmic Vesicle Secretory Vesicle Membrane Single-Pass Membrane Protein Secretory Vesicle Synaptic Vesicle Membrane Chromaffin Granule Membrane Cytoplasm
Alternative Antibody Names	Anti-Synaptotagmin-1 antibody Anti-Synaptotagmin I antibody Anti-Syti antibody Anti-P65 antibody Anti-SYT1 antibody Anti-SVP65 antibody Anti-SYT antibody

Information sourced from Uniprot.org