• STJ70471 (0. 01µg/ml) staining of Human Muscle lysate (35µg protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-Syntrophin antibody (N-Term) (STJ70471)

SKU:
STJ70471-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Mouse/Rat/Dog/Pig/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-Syntrophin (N-Term) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-1-3µg/ml
ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: SNTA1
Gene ID: 6640
Uniprot ID: SNTA1_HUMAN
Immunogen Region: N-Term
Accession Number: NP_003089.1
Immunogen Sequence: ASGRRAPRTGLLE
Post Translational Modifications Phosphorylated by CaM-kinase II. Phosphorylation may inhibit the interaction with DMD.
Function Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5-bisphosphate.
Protein Name Alpha-1-Syntrophin
59 Kda Dystrophin-Associated Protein A1 Acidic Component 1
Pro-Tgf-Alpha Cytoplasmic Domain-Interacting Protein 1
Tacip1
Syntrophin-1
Cellular Localisation Cell Membrane
Sarcolemma
Peripheral Membrane Protein
Cytoplasmic Side
Cell Junction
Cytoplasm
Cytoskeleton
In Skeletal Muscle
It Localizes At The Cytoplasmic Side Of The Sarcolemmal Membrane And At Neuromuscular Junctions
Alternative Antibody Names Anti-Alpha-1-Syntrophin antibody
Anti-59 Kda Dystrophin-Associated Protein A1 Acidic Component 1 antibody
Anti-Pro-Tgf-Alpha Cytoplasmic Domain-Interacting Protein 1 antibody
Anti-Tacip1 antibody
Anti-Syntrophin-1 antibody
Anti-SNTA1 antibody
Anti-SNT1 antibody

Information sourced from Uniprot.org

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