Anti-Syntrophin antibody (N-Term) (STJ70471)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Syntrophin (N-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Pig/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 60kDa band observed in Human and Mouse Muscle lysates and in rodent Heart lysates (calculated MW of 53.9kDa according to Human NP_003089.1). Recommended concentration: 1-3ยตg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SNTA1 |
| Gene ID | 6640 |
| Uniprot ID | SNTA1_HUMAN |
| Accession Number | NP_003089.1 |
| Immunogen Region | N-Term |
| Immunogen Sequence | ASGRRAPRTGLLE |
Additional Info
| Post Translational Modifications | Phosphorylated by CaM-kinase II. Phosphorylation may inhibit the interaction with DMD. |
| Function | Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5-bisphosphate. |
| Protein Name | Alpha-1-Syntrophin59 Kda Dystrophin-Associated Protein A1 Acidic Component 1Pro-Tgf-Alpha Cytoplasmic Domain-Interacting Protein 1Tacip1Syntrophin-1 |
| Cellular Localisation | Cell MembraneSarcolemmaPeripheral Membrane ProteinCytoplasmic SideCell JunctionCytoplasmCytoskeletonIn Skeletal MuscleIt Localizes At The Cytoplasmic Side Of The Sarcolemmal Membrane And At Neuromuscular Junctions |
| Alternative Antibody Names | Anti-Alpha-1-Syntrophin antibodyAnti-59 Kda Dystrophin-Associated Protein A1 Acidic Component 1 antibodyAnti-Pro-Tgf-Alpha Cytoplasmic Domain-Interacting Protein 1 antibodyAnti-Tacip1 antibodyAnti-Syntrophin-1 antibodyAnti-SNTA1 antibodyAnti-SNT1 antibody |
Information sourced from Uniprot.org