| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SYNJ1 |
| Gene ID: | 8867 |
| Uniprot ID: | SYNJ1_HUMAN |
| Immunogen Region: | 100-200 |
| Immunogen Sequence: | GLLGVLRLNLGDTMLHYLVL VTGCMSVGKIQESEVFRVTS TEFISLRIDSSDEDRISEVR KVLNSGNFYFAWSASGISLD LSLNAHRSMQEQTTDNRFFW N |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human SYNJ1 (NP_003886.3). |
| Function | Phosphatase that acts on various phosphoinositides, including phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)-bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate. Has a role in clathrin-mediated endocytosis. Hydrolyzes PIP2 bound to actin regulatory proteins resulting in the rearrangement of actin filaments downstream of tyrosine kinase and ASH/GRB2. |
| Protein Name | Synaptojanin-1Synaptic Inositol 1 -4 -5-Trisphosphate 5-Phosphatase 1 |
| Database Links | Reactome: R-HSA-1660499Reactome: R-HSA-1855183Reactome: R-HSA-1855204Reactome: R-HSA-8856828 |
| Cellular Localisation | CytoplasmPerinuclear Region |
| Alternative Antibody Names | Anti-Synaptojanin-1 antibodyAnti-Synaptic Inositol 1 -4 -5-Trisphosphate 5-Phosphatase 1 antibodyAnti-SYNJ1 antibodyAnti-KIAA0910 antibody |
Information sourced from Uniprot.org
