Anti-SYNJ1 antibody (100-200) (STJ119653)

Name: Anti-SYNJ1 antibody (100-200) (STJ119653)
SKU: STJ119653
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ119653

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Short Description	Rabbit polyclonal SYNJ1 (100-200) antibody for use in WB and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	SYNJ1
Gene ID	8867
Uniprot ID	SYNJ1_HUMAN
Immunogen Region	100-200
Immunogen Sequence	GLLGVLRLNLGDTMLHYLVL VTGCMSVGKIQESEVFRVTS TEFISLRIDSSDEDRISEVR KVLNSGNFYFAWSASGISLD LSLNAHRSMQEQTTDNRFFW N
Specificity	A synthetic peptide corresponding to a sequence within amino acids 100-200 of human SYNJ1 (NP_003886.3).

Function	Phosphatase that acts on various phosphoinositides, including phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)-bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate. Has a role in clathrin-mediated endocytosis. Hydrolyzes PIP2 bound to actin regulatory proteins resulting in the rearrangement of actin filaments downstream of tyrosine kinase and ASH/GRB2.
Protein Name	Synaptojanin-1 Synaptic Inositol 1 -4 -5-Trisphosphate 5-Phosphatase 1
Database Links	Reactome: R-HSA-1660499 Reactome: R-HSA-1855183 Reactome: R-HSA-1855204 Reactome: R-HSA-8856828
Cellular Localisation	Cytoplasm Perinuclear Region
Alternative Antibody Names	Anti-Synaptojanin-1 antibody Anti-Synaptic Inositol 1 -4 -5-Trisphosphate 5-Phosphatase 1 antibody Anti-SYNJ1 antibody Anti-KIAA0910 antibody

Information sourced from Uniprot.org