Anti-Synaptotagmin-3 antibody (25-38) (STJ72830)

SKU:
STJ72830-100

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Host: Goat
Applications: Pep-ELISA
Reactivity: Human/Mouse/Rat/Dog/Pig/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-Synaptotagmin-3 (25-38) is suitable for use in ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: ELISA-antibody detection limit dilution 1:128000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: SYT3
Gene ID: 84258
Uniprot ID: SYT3_HUMAN
Immunogen Region: 25-38
Accession Number: NP_115674.1
Specificity: Reported variants represent identical protein: NP_001153801.1, NP_001153800.1, NP_115674.1. The immunizing peptide represents part of the vesicular domain.
Immunogen Sequence: RDADTNDRCQEFN
Function Ca(2+) sensor involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain. Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes.both actions contribute to triggering exocytosis. Plays a role in dendrite formation by melanocytes.
Protein Name Synaptotagmin-3
Synaptotagmin Iii
Sytiii
Cellular Localisation Cell Membrane
Single-Pass Membrane Protein
Cytoplasmic Vesicle
Secretory Vesicle Membrane
Alternative Antibody Names Anti-Synaptotagmin-3 antibody
Anti-Synaptotagmin Iii antibody
Anti-Sytiii antibody
Anti-SYT3 antibody

Information sourced from Uniprot.org

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