| Short Description : | Goat polyclonal antibody anti-Synaptotagmin-3 (25-38) is suitable for use in ELISA research applications. |
| Applications: | Pep-ELISA |
| Host: | Goat |
| Reactivity: | Human/Mouse/Rat/Dog/Pig/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Preliminary experiments in Human, Mouse and Rat Brain lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). We would appreciate any feedback fro |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SYT3 |
| Gene ID: | 84258 |
| Uniprot ID: | SYT3_HUMAN |
| Accession Number: | NP_115674.1 |
| Immunogen Region: | 25-38 |
| Immunogen Sequence: | RDADTNDRCQEFN |
| Specificity: | Reported variants represent identical protein: NP_001153801.1, NP_001153800.1, NP_115674.1. The immunizing peptide represents part of the vesicular domain. |
| Function | Ca(2+) sensor involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain. Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes.both actions contribute to triggering exocytosis. Plays a role in dendrite formation by melanocytes. |
| Protein Name | Synaptotagmin-3Synaptotagmin IiiSytiii |
| Cellular Localisation | Cell MembraneSingle-Pass Membrane ProteinCytoplasmic VesicleSecretory Vesicle Membrane |
| Alternative Antibody Names | Anti-Synaptotagmin-3 antibodyAnti-Synaptotagmin Iii antibodyAnti-Sytiii antibodyAnti-SYT3 antibody |
Information sourced from Uniprot.org