Anti-Synapsin 2 antibody (420-470) (STJ13100350)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 420-470 of human Synapsin-2 conjugated to blue carrier protein was used as the antigen. The peptide shares 90% identity with mouse and rat sequences.
General Information
| Short Description | Rabbit polyclonal anti-Synapsin 2 (420-470) for use in IHC-P and WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P/WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC-P, WB. A dilution of 1:1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | SYN2 |
| Gene ID | 6854 |
| Uniprot ID | SYN2_HUMAN |
| Immunogen | A synthetic peptide from aa region 420-470 of human Synapsin-2 conjugated to blue carrier protein was used as the antigen. The peptide shares 90% identity with mouse and rat sequences. |
| Immunogen Region | 420-470 |
| Specificity | Specific for Synapsin-2. |
Additional Info
| Post Translational Modifications | Phosphorylation at Ser-10 dissociates synapsins from synaptic vesicles. Phosphorylation at Ser-425 by MAPK1/ERK2 and/or MAPK3/ERK1 may play a role in noradrenaline secretion by sympathetic neurons. |
| Function | Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. May play a role in noradrenaline secretion by sympathetic neurons. |
| Protein Name | Synapsin-2Synapsin Ii |
| Database Links | Reactome: R-HSA-181429Reactome: R-HSA-212676 |
| Cellular Localisation | Synapse |
| Alternative Antibody Names | Anti-Synapsin-2 antibodyAnti-Synapsin Ii antibodyAnti-SYN2 antibody |
Information sourced from Uniprot.org