• Western blot analysis of extracts of various cell lines, using (STJ29298) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-SYCE1 antibody (132-351) (STJ29298)

SKU:
STJ29298

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SYCE1 (132-351) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SYCE1
Gene ID: 93426
Uniprot ID: SYCE1_HUMAN
Immunogen Region: 132-351
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 132-351 of human SYCE1 (NP_001137236.1).
Immunogen Sequence: ECKERISALNLQIEEEKNKQ RQLRLAFEEQLEDLMGQHKD LWDFHMPERLAKEICALDSS KEQLLKEEKLVKATLEDVKH QLCSLCGAEGPSTLDEGLFL RSQEAAATVQLFQEEHRKAE ELLAAAAQRHQQLQQKCQQQ QQKRQRLKEELEKHGMQVPA QAQSTQEEEAGPGDVASPKP LKGERPGAAHQAGPDVLIGQ EDTLHPDLSPRGFQEIKELF
Function Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central element. May have a role in the synaptonemal complex assembly, stabilization and recombination.
Protein Name Synaptonemal Complex Central Element Protein 1
Cancer/Testis Antigen 76
Ct76
Database Links Reactome: R-HSA-1221632
Cellular Localisation Nucleus
Chromosome
Associates With Chromatin
In Prophase I Stage Of Meiosis
Localizes In The Transverse Central Elements Of The Central Region Between Lateral Elements Of The Synaptonemal Complexes
Found Only Where The Chromosome Cores Are Synapsed
Colocalizes With Syce2 In The Central Elements
Alternative Antibody Names Anti-Synaptonemal Complex Central Element Protein 1 antibody
Anti-Cancer/Testis Antigen 76 antibody
Anti-Ct76 antibody
Anti-SYCE1 antibody
Anti-C10orf94 antibody

Information sourced from Uniprot.org

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