| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SYCE1 |
| Gene ID: | 93426 |
| Uniprot ID: | SYCE1_HUMAN |
| Immunogen Region: | 132-351 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 132-351 of human SYCE1 (NP_001137236.1). |
| Immunogen Sequence: | ECKERISALNLQIEEEKNKQ RQLRLAFEEQLEDLMGQHKD LWDFHMPERLAKEICALDSS KEQLLKEEKLVKATLEDVKH QLCSLCGAEGPSTLDEGLFL RSQEAAATVQLFQEEHRKAE ELLAAAAQRHQQLQQKCQQQ QQKRQRLKEELEKHGMQVPA QAQSTQEEEAGPGDVASPKP LKGERPGAAHQAGPDVLIGQ EDTLHPDLSPRGFQEIKELF |
| Function | Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central element. May have a role in the synaptonemal complex assembly, stabilization and recombination. |
| Protein Name | Synaptonemal Complex Central Element Protein 1 Cancer/Testis Antigen 76 Ct76 |
| Database Links | Reactome: R-HSA-1221632 |
| Cellular Localisation | Nucleus Chromosome Associates With Chromatin In Prophase I Stage Of Meiosis Localizes In The Transverse Central Elements Of The Central Region Between Lateral Elements Of The Synaptonemal Complexes Found Only Where The Chromosome Cores Are Synapsed Colocalizes With Syce2 In The Central Elements |
| Alternative Antibody Names | Anti-Synaptonemal Complex Central Element Protein 1 antibody Anti-Cancer/Testis Antigen 76 antibody Anti-Ct76 antibody Anti-SYCE1 antibody Anti-C10orf94 antibody |
Information sourced from Uniprot.org