Anti-Swiprosin 1/EFHD2 antibody (C-Term) (STJ70621)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Swiprosin 1/EFHD2 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 30kDa band observed in Human Thymus, Human Lymph node and Human Tonsil lysates (calculated MW of 26.7kDa according to NP_077305.2). Recommended concentration: 0.5-1.5µg/ml. Pri |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | EFHD2 |
| Gene ID | 79180 |
| Uniprot ID | EFHD2_HUMAN |
| Accession Number | NP_077305.2 |
| Immunogen Region | C-Term |
| Immunogen Sequence | CAAFKELQSTFK |
| Specificity | This antibody does not cross-react with Mouse Swiprosin 2. Data kindly provided by Sebastian Duetting and Dirk Mielenz. |
Additional Info
| Function | May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. |
| Protein Name | Ef-Hand Domain-Containing Protein D2Swiprosin-1 |
| Database Links | Reactome: R-HSA-9013405 |
| Cellular Localisation | Membrane RaftIn A Mouse Immature B-Cell Line Wehi-231 |
| Alternative Antibody Names | Anti-Ef-Hand Domain-Containing Protein D2 antibodyAnti-Swiprosin-1 antibodyAnti-EFHD2 antibodyAnti-SWS1 antibody |
Information sourced from Uniprot.org