| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-SUMF1 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 37-40kDa band observed in Mouse Pancreas, Mouse Eye and Human Kidney lysates (calculated MW of 40.6kDa according to Human NP_877437.2 and 40.6kDa according to Mouse NP_666049.2) |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SUMF1 |
| Gene ID: | 285362 |
| Uniprot ID: | SUMF1_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_877437.2 |
| Immunogen Sequence: | ETLNPKGPPSGKDR |
| Post Translational Modifications | N-glycosylated. Contains high-mannose-type oligosaccharides. |
| Function | Oxidase that catalyzes the conversion of cysteine to 3-oxoalanine on target proteins, using molecular oxygen and an unidentified reducing agent. 3-oxoalanine modification, which is also named formylglycine (fGly), occurs in the maturation of arylsulfatases and some alkaline phosphatases that use the hydrated form of 3-oxoalanine as a catalytic nucleophile. Known substrates include GALNS, ARSA, STS and ARSE. |
| Protein Name | Formylglycine-Generating EnzymeFgeC-Alpha-Formylglycine-Generating Enzyme 1Sulfatase-Modifying Factor 1 |
| Database Links | Reactome: R-HSA-1663150Reactome: R-HSA-9840310 |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Antibody Names | Anti-Formylglycine-Generating Enzyme antibodyAnti-Fge antibodyAnti-C-Alpha-Formylglycine-Generating Enzyme 1 antibodyAnti-Sulfatase-Modifying Factor 1 antibodyAnti-SUMF1 antibodyAnti-PSEC0152 antibodyAnti-UNQ3037 antibodyAnti-PRO9852 antibody |
Information sourced from Uniprot.org