Anti-SUMF1 antibody (Internal) (STJ72015)

SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
STJ72015-100
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General Information

Short DescriptionGoat polyclonal antibody anti-SUMF1 (Internal) is suitable for use in ELISA and Western Blot research applications.
ApplicationsPep-ELISA/WB
HostGoat
ReactivityHuman/Mouse/Rat/Dog/Cow
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration0.5 mg/mL
PurificationPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution RangePeptide ELISA: antibody detection limit dilution 1:16000.
WB: Approx 37-40kDa band observed in Mouse Pancreas, Mouse Eye and Human Kidney lysates (calculated MW of 40.6kDa according to Human NP_877437.2 and 40.6kDa according to Mouse NP_666049.2)
Formulation0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage InstructionStore at-20°C on receipt and minimise freeze-thaw cycles.

Target Information

Gene SymbolSUMF1
Gene ID285362
Uniprot IDSUMF1_HUMAN
Accession NumberNP_877437.2
Immunogen RegionInternal
Immunogen SequenceETLNPKGPPSGKDR

Additional Info

Post Translational Modifications N-glycosylated. Contains high-mannose-type oligosaccharides.
Function Oxidase that catalyzes the conversion of cysteine to 3-oxoalanine on target proteins, using molecular oxygen and an unidentified reducing agent. 3-oxoalanine modification, which is also named formylglycine (fGly), occurs in the maturation of arylsulfatases and some alkaline phosphatases that use the hydrated form of 3-oxoalanine as a catalytic nucleophile. Known substrates include GALNS, ARSA, STS and ARSE.
Protein Name Formylglycine-Generating Enzyme
Fge
C-Alpha-Formylglycine-Generating Enzyme 1
Sulfatase-Modifying Factor 1
Database Links Reactome: R-HSA-1663150
Reactome: R-HSA-9840310
Cellular Localisation Endoplasmic Reticulum Lumen
Alternative Antibody Names Anti-Formylglycine-Generating Enzyme antibody
Anti-Fge antibody
Anti-C-Alpha-Formylglycine-Generating Enzyme 1 antibody
Anti-Sulfatase-Modifying Factor 1 antibody
Anti-SUMF1 antibody
Anti-PSEC0152 antibody
Anti-UNQ3037 antibody
Anti-PRO9852 antibody

Information sourced from Uniprot.org

Citations

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