| Post Translational Modifications | Phosphorylated. |
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation. Responsible for the sulfation of cholesterol. Catalyzes sulfation of the 3beta-hydroxyl groups of steroids, such as, pregnenolone and dehydroepiandrosterone (DHEA). Preferentially sulfonates cholesterol, while it has also significant activity with pregnenolone and DHEA. Plays a role in epidermal cholesterol metabolism and in the regulation of epidermal proliferation and differentiation. Isoform 2: Sulfonates pregnenolone but not cholesterol. |
| Protein Name | Sulfotransferase 2b1Alcohol SulfotransferaseHydroxysteroid Sulfotransferase 2Sulfotransferase Family 2b Member 1Sulfotransferase Family Cytosolic 2b Member 1St2b1 |
| Database Links | Reactome: R-HSA-156584 |
| Cellular Localisation | CytoplasmCytosolMicrosomeNucleusPhosphorylation Of Ser-348 Is Required For Translocation To The Nucleus |
| Alternative Antibody Names | Anti-Sulfotransferase 2b1 antibodyAnti-Alcohol Sulfotransferase antibodyAnti-Hydroxysteroid Sulfotransferase 2 antibodyAnti-Sulfotransferase Family 2b Member 1 antibodyAnti-Sulfotransferase Family Cytosolic 2b Member 1 antibodyAnti-St2b1 antibodyAnti-SULT2B1 antibodyAnti-HSST2 antibody |
Information sourced from Uniprot.org
