Anti-SULT2B1 antibody (STJA0008588)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human SULT2B1
General Information
| Short Description | Rabbit polyclonal anti-Sulfotransferase 2B1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SULT2B1 |
| Gene ID | 6820 |
| Uniprot ID | ST2B1_HUMAN |
| Immunogen | Synthesized peptide derived from human SULT2B1 |
| Specificity | This antibody detects endogenous levels of SULT2B1 at Human, Mouse, Rat |
Additional Info
| Post Translational Modifications | Phosphorylated. |
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation. Responsible for the sulfation of cholesterol. Catalyzes sulfation of the 3beta-hydroxyl groups of steroids, such as, pregnenolone and dehydroepiandrosterone (DHEA). Preferentially sulfonates cholesterol, while it also has significant activity with pregnenolone and DHEA. Plays a role in epidermal cholesterol metabolism and in the regulation of epidermal proliferation and differentiation. Isoform 2: Sulfonates pregnenolone but not cholesterol. |
| Protein Name | Sulfotransferase 2b1Alcohol SulfotransferaseHydroxysteroid Sulfotransferase 2Sulfotransferase Family 2b Member 1Sulfotransferase Family Cytosolic 2b Member 1St2b1 |
| Database Links | Reactome: R-HSA-156584 |
| Cellular Localisation | CytoplasmCytosolMicrosomeNucleusPhosphorylation Of Ser-348 Is Required For Translocation To The Nucleus |
| Alternative Antibody Names | Anti-Sulfotransferase 2b1 antibodyAnti-Alcohol Sulfotransferase antibodyAnti-Hydroxysteroid Sulfotransferase 2 antibodyAnti-Sulfotransferase Family 2b Member 1 antibodyAnti-Sulfotransferase Family Cytosolic 2b Member 1 antibodyAnti-St2b1 antibodyAnti-SULT2B1 antibodyAnti-HSST2 antibody |
Information sourced from Uniprot.org