Anti-STXBP3 antibody (343-592) (STJ110452)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal STXBP3 (343-592) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | STXBP3 |
| Gene ID | 6814 |
| Uniprot ID | STXB3_HUMAN |
| Immunogen Region | 343-592 |
| Immunogen Sequence | KQVVHLNLAEDCMNKFKLNI EKLCKTEQDLALGTDAEGQK VKDSMRVLLPVLLNKNHDNC DKIRAILLYIFSINGTTEEN LDRLIQNVKIENESDMIRNW SYLGVPIVPQSQQGKPLRKD RSAEETFQLSRWTPFIKDIM EDAIDNRLDSKEWPYCSQCP AVWNGSGAVSARQKPRANYL EDRKNGSKLIVFVIGGITYS EVRCAYEVSQAHKSCEVIIG STHVLTPKKLLDDIKMLNK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 343-592 of human STXBP3 (NP_009200.2). |
Additional Info
| Tissue Specificity | Megakaryocytes and platelets. |
| Post Translational Modifications | Phosphorylated by PKC in platelets in response to thrombin stimulation.phosphorylation inhibits binding to STX4. |
| Function | Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. |
| Protein Name | Syntaxin-Binding Protein 3Platelet Sec1 ProteinPspProtein Unc-18 Homolog 3Unc18-3Protein Unc-18 Homolog CUnc-18c |
| Database Links | Reactome: R-HSA-114516Reactome: R-HSA-1445148 |
| Cellular Localisation | CytoplasmCytosolCell MembraneIn PlateletsPredominantly CytosolicLow Amounts Membrane-Associated |
| Alternative Antibody Names | Anti-Syntaxin-Binding Protein 3 antibodyAnti-Platelet Sec1 Protein antibodyAnti-Psp antibodyAnti-Protein Unc-18 Homolog 3 antibodyAnti-Unc18-3 antibodyAnti-Protein Unc-18 Homolog C antibodyAnti-Unc-18c antibodyAnti-STXBP3 antibody |
Information sourced from Uniprot.org