• Western blot analysis of extracts of various cell lines, using STXBP3 antibody (STJ110452) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
  • Western blot analysis of extracts of various cell lines, using STXBP3 antibody (STJ110452) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-STXBP3 antibody (343-592) (STJ110452)

SKU:
STJ110452

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-STXBP3 (343-592) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: STXBP3
Gene ID: 6814
Uniprot ID: STXB3_HUMAN
Immunogen Region: 343-592
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 343-592 of human STXBP3 (NP_009200.2).
Immunogen Sequence: KQVVHLNLAEDCMNKFKLNI EKLCKTEQDLALGTDAEGQK VKDSMRVLLPVLLNKNHDNC DKIRAILLYIFSINGTTEEN LDRLIQNVKIENESDMIRNW SYLGVPIVPQSQQGKPLRKD RSAEETFQLSRWTPFIKDIM EDAIDNRLDSKEWPYCSQCP AVWNGSGAVSARQKPRANYL EDRKNGSKLIVFVIGGITYS EVRCAYEVSQAHKSCEVIIG STHVLTPKKLLDDIKMLNK
Tissue Specificity Megakaryocytes and platelets.
Post Translational Modifications Phosphorylated by PKC in platelets in response to thrombin stimulation.phosphorylation inhibits binding to STX4.
Function Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.
Protein Name Syntaxin-Binding Protein 3
Platelet Sec1 Protein
Psp
Protein Unc-18 Homolog 3
Unc18-3
Protein Unc-18 Homolog C
Unc-18c
Database Links Reactome: R-HSA-114516
Reactome: R-HSA-1445148
Cellular Localisation Cytoplasm
Cytosol
Cell Membrane
In Platelets
Predominantly Cytosolic
Low Amounts Membrane-Associated
Alternative Antibody Names Anti-Syntaxin-Binding Protein 3 antibody
Anti-Platelet Sec1 Protein antibody
Anti-Psp antibody
Anti-Protein Unc-18 Homolog 3 antibody
Anti-Unc18-3 antibody
Anti-Protein Unc-18 Homolog C antibody
Anti-Unc-18c antibody
Anti-STXBP3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance