Anti-Stearoyl-CoA desaturase antibody (C-Term) (STJ70860)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Stearoyl-CoA desaturase (C-Term) is suitable for use in ELISA, Immunohistochemistry and Flow Cytometry research applications. |
| Applications | Pep-ELISA/IHC/FC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Preliminary experiments gave an approx 30kDa band in Human Adipose, Brain and Liver lysates after 0.3 ยตg/ml antibody staining. Please note that currently we cannot find an explanation |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SCD |
| Gene ID | 6319 |
| Uniprot ID | SCD_HUMAN |
| Accession Number | NP_005054.3 |
| Immunogen Region | C-Term |
| Immunogen Sequence | RIKRTGDGNYKSG |
Additional Info
| Function | Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA. Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation. Plays an important role in body energy homeostasis. Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides. |
| Protein Name | Stearoyl-Coa DesaturaseHscd1Acyl-Coa DesaturaseDelta(9-DesaturaseDelta-9 DesaturaseFatty Acid Desaturase |
| Database Links | Reactome: R-HSA-2426168Reactome: R-HSA-75105Reactome: R-HSA-9029558 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Stearoyl-Coa Desaturase antibodyAnti-Hscd1 antibodyAnti-Acyl-Coa Desaturase antibodyAnti-Delta(9-Desaturase antibodyAnti-Delta-9 Desaturase antibodyAnti-Fatty Acid Desaturase antibodyAnti-SCD antibodyAnti-FADS5 antibodyAnti-SCD1 antibodyAnti-SCDOS antibody |
Information sourced from Uniprot.org