• STJ70860 (2. 5ul) staining of HepG2 cells mixed in with PBL. Detected by fluorescence with PE for SCD in green and with OC515 for CD45 (CYT-450C) in red.

Anti-Stearoyl-CoA desaturase antibody (C-Term) (STJ70860)

SKU:
STJ70860-100

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Host: Goat
Applications: Pep-ELISA/IHC/FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-Stearoyl-CoA desaturase (C-Term) is suitable for use in ELISA, Immunohistochemistry and Flow Cytometry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: IHC-5µg/ml
ELISA-antibody detection limit dilution 1:64000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: SCD
Gene ID: 6319
Uniprot ID: SCD_HUMAN
Immunogen Region: C-Term
Accession Number: NP_005054.3
Immunogen Sequence: RIKRTGDGNYKSG
Function Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA. Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation. Plays an important role in body energy homeostasis. Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides.
Protein Name Stearoyl-Coa Desaturase
Hscd1
Acyl-Coa Desaturase
Delta(9-Desaturase
Delta-9 Desaturase
Fatty Acid Desaturase
Database Links Reactome: R-HSA-2426168
Reactome: R-HSA-75105
Reactome: R-HSA-9029558
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Stearoyl-Coa Desaturase antibody
Anti-Hscd1 antibody
Anti-Acyl-Coa Desaturase antibody
Anti-Delta(9-Desaturase antibody
Anti-Delta-9 Desaturase antibody
Anti-Fatty Acid Desaturase antibody
Anti-SCD antibody
Anti-FADS5 antibody
Anti-SCD1 antibody
Anti-SCDOS antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance