Anti-STAU1 antibody (557-570 aa) [R03-3G2] (STJA0012004)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human Staufen
General Information
| Short Description | Rabbit monoclonal anti-Staufen (557-570 aa) for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R03-3G2 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100 |
| Formulation | 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | STAU1 |
| Gene ID | 6780 |
| Uniprot ID | STAU1_HUMAN |
| Immunogen | A synthetic peptide of human Staufen |
| Immunogen Region | 557-570 aa |
Additional Info
| Tissue Specificity | Widely expressed. Expressed in brain, pancreas, heart, skeletal muscles, liver, lung, kidney and placenta. |
| Function | Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site. (Microbial infection) Plays a role in virus particles production of many viruses including of HIV-1, HERV-K, ebola virus and influenza virus. Acts by interacting with various viral proteins involved in particle budding process. |
| Protein Name | Double-Stranded Rna-Binding Protein Staufen Homolog 1 |
| Database Links | |
| Cellular Localisation | CytoplasmRough Endoplasmic ReticulumLocalizes Exclusively With The Rough Endoplasmic Reticulum (Rer) |
| Alternative Antibody Names | Anti-Double-Stranded Rna-Binding Protein Staufen Homolog 1 antibodyAnti-STAU1 antibodyAnti-STAU antibody |
Information sourced from Uniprot.org