Anti-STAU1 antibody (557-570 aa) [R03-3G2] (STJA0012004)

SKU:
STJA0012004-100
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Short Description :Rabbit monoclonal anti-Staufen (557-570 aa) for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC-P
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :R03-3G2
Isotype:IgG
Conjugation:Unconjugated
Concentration:0.3 mg/mL
Purification:Affinity Purified
Dilution Range:WB 1:500-1:1000
IHC 1:50-1:100
Formulation:50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:STAU1
Gene ID:6780
Uniprot ID:STAU1_HUMAN
Immunogen:A synthetic peptide of human Staufen
Immunogen Region:557-570 aa
Tissue Specificity Widely expressed. Expressed in brain, pancreas, heart, skeletal muscles, liver, lung, kidney and placenta.
Function Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site. (Microbial infection) Plays a role in virus particles production of many viruses including of HIV-1, HERV-K, ebola virus and influenza virus. Acts by interacting with various viral proteins involved in particle budding process.
Protein Name Double-Stranded Rna-Binding Protein Staufen Homolog 1
Database Links
Cellular Localisation Cytoplasm
Rough Endoplasmic Reticulum
Localizes Exclusively With The Rough Endoplasmic Reticulum (Rer)
Alternative Antibody Names Anti-Double-Stranded Rna-Binding Protein Staufen Homolog 1 antibody
Anti-STAU1 antibody
Anti-STAU antibody

Information sourced from Uniprot.org