| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | STAU1 |
| Gene ID: | 6780 |
| Uniprot ID: | STAU1_HUMAN |
| Immunogen Region: | 426-577 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 426-577 of human Staufen (NP_059347.2). |
| Immunogen Sequence: | QAVGVSQGHHTKDFTRAAPN PAKATVTAMIARELLYGGTS PTAETILKNNISSGHVPHGP LTRPSEQLDYLSRVQGFQVE YKDFPKNNKNEFVSLINCSS QPPLISHGIGKDVESCHDMA ALNILKLLSELDQQSTEMPR TGNGPMSVCGRC |
| Tissue Specificity | Widely expressed. Expressed in brain, pancreas, heart, skeletal muscles, liver, lung, kidney and placenta. |
| Function | Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site. (Microbial infection) Plays a role in virus particles production of many viruses including of HIV-1, HERV-K, ebola virus and influenza virus. Acts by interacting with various viral proteins involved in particle budding process. |
| Protein Name | Double-Stranded Rna-Binding Protein Staufen Homolog 1 |
| Cellular Localisation | CytoplasmRough Endoplasmic ReticulumLocalizes Exclusively With The Rough Reticulum Endoplasmic (Rer) |
| Alternative Antibody Names | Anti-Double-Stranded Rna-Binding Protein Staufen Homolog 1 antibodyAnti-STAU1 antibodyAnti-STAU antibody |
Information sourced from Uniprot.org
