| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-STAU1 (426-577) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:100-1:500IHC-P 1:50-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
STAU1 |
| Gene ID: |
6780 |
| Uniprot ID: |
STAU1_HUMAN |
| Immunogen Region: |
426-577 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 426-577 of human Staufen (NP_059347.2). |
| Immunogen Sequence: |
QAVGVSQGHHTKDFTRAAPN PAKATVTAMIARELLYGGTS PTAETILKNNISSGHVPHGP LTRPSEQLDYLSRVQGFQVE YKDFPKNNKNEFVSLINCSS QPPLISHGIGKDVESCHDMA ALNILKLLSELDQQSTEMPR TGNGPMSVCGRC |
| Tissue Specificity | Widely expressed. Expressed in brain, pancreas, heart, skeletal muscles, liver, lung, kidney and placenta. |
| Function | Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site. (Microbial infection) Plays a role in virus particles production of many viruses including of HIV-1, HERV-K, ebola virus and influenza virus. Acts by interacting with various viral proteins involved in particle budding process. |
| Protein Name | Double-Stranded Rna-Binding Protein Staufen Homolog 1 |
| Cellular Localisation | CytoplasmRough Endoplasmic ReticulumLocalizes Exclusively With The Rough Reticulum Endoplasmic (Rer) |
| Alternative Antibody Names | Anti-Double-Stranded Rna-Binding Protein Staufen Homolog 1 antibodyAnti-STAU1 antibodyAnti-STAU antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
