Host: |
Mouse |
Applications: |
IHC-P |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-STAT6 is suitable for use in Immunohistochemistry research applications. |
Clonality: |
Monoclonal |
Clone ID: |
D1 |
Conjugation: |
Unconjugated |
Isotype: |
IgG2b |
Formulation: |
PBS Buffer, with less than 0.1% sodium azide and 0.1% gelatin |
Purification: |
Concentrate |
Dilution Range: |
IHC-P 1:100-1:200 |
Storage Instruction: |
Store at 2-8°C upon receipt. |
Post Translational Modifications | Tyrosine phosphorylated on Tyr-641 following stimulation by IL4/interleukin-4. Tyrosine phosphorylated following stimulation by IL3/interleukin-3. Dephosphorylation on tyrosine residues by PTPN2 negatively regulates the IL4/interleukin-4 mediated signaling. Mono-ADP-ribosylated by PARP14. |
Function | Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling. |
Protein Name | Signal Transducer And Activator Of Transcription 6Il-4 Stat |
Database Links | Reactome: R-HSA-186763Reactome: R-HSA-3249367Reactome: R-HSA-6785807 |
Cellular Localisation | CytoplasmNucleusTranslocated Into The Nucleus In Response To Phosphorylation |
Alternative Antibody Names | Anti-Signal Transducer And Activator Of Transcription 6 antibodyAnti-Il-4 Stat antibodyAnti-STAT6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance