Anti-STAT6 antibody [D1] (STJ16101849)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2b
General Information
| Short Description | Mouse monoclonal anti-STAT6 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | D1 |
| Isotype | IgG2b |
| Conjugation | Unconjugated |
| Purification | Concentrate |
| Dilution Range | IHC-P 1:100-1:200 |
| Formulation | PBS Buffer, with less than 0.1% sodium azide and 0.1% gelatin |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Gene Symbol | STAT6 |
| Gene ID | 6778 |
| Uniprot ID | STAT6_HUMAN |
Additional Info
| Post Translational Modifications | Tyrosine phosphorylated on Tyr-641 following stimulation by IL4/interleukin-4. Tyrosine phosphorylated following stimulation by IL3/interleukin-3. Dephosphorylation on tyrosine residues by PTPN2 negatively regulates the IL4/interleukin-4 mediated signaling. Mono-ADP-ribosylated by PARP14. |
| Function | Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling. |
| Protein Name | Signal Transducer And Activator Of Transcription 6Il-4 Stat |
| Database Links | Reactome: R-HSA-186763Reactome: R-HSA-3249367Reactome: R-HSA-6785807 |
| Cellular Localisation | CytoplasmNucleusTranslocated Into The Nucleus In Response To Phosphorylation |
| Alternative Antibody Names | Anti-Signal Transducer And Activator Of Transcription 6 antibodyAnti-Il-4 Stat antibodyAnti-STAT6 antibody |
Information sourced from Uniprot.org