Anti-STAT6 antibody [D1] (STJ16101849)

SKU:
STJ16101849-1

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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-STAT6 is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: D1
Conjugation: Unconjugated
Isotype: IgG2b
Formulation: PBS Buffer, with less than 0.1% sodium azide and 0.1% gelatin
Purification: Concentrate
Dilution Range: IHC-P 1:100-1:200
Storage Instruction: Store at 2-8°C upon receipt.
Gene Symbol: STAT6
Gene ID: 6778
Uniprot ID: STAT6_HUMAN
Post Translational Modifications Tyrosine phosphorylated on Tyr-641 following stimulation by IL4/interleukin-4. Tyrosine phosphorylated following stimulation by IL3/interleukin-3. Dephosphorylation on tyrosine residues by PTPN2 negatively regulates the IL4/interleukin-4 mediated signaling. Mono-ADP-ribosylated by PARP14.
Function Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling.
Protein Name Signal Transducer And Activator Of Transcription 6
Il-4 Stat
Database Links Reactome: R-HSA-186763
Reactome: R-HSA-3249367
Reactome: R-HSA-6785807
Cellular Localisation Cytoplasm
Nucleus
Translocated Into The Nucleus In Response To Phosphorylation
Alternative Antibody Names Anti-Signal Transducer And Activator Of Transcription 6 antibody
Anti-Il-4 Stat antibody
Anti-STAT6 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance