| Tissue Specificity | Adult pituitary gland, heart, small intestine, adrenal gland, cerebellum and fetal hypothalamus. No expression in fetal or adult kidney, liver, pancreas, uterus, spleen, lung, thyroid or ovary. |
| Post Translational Modifications | Palmitoylated by ZDHHC5, but not ZDHHC3, nor ZDHHC8. Palmitoylation creates an additional intracellular loop which is thought to be important for efficient coupling to G-proteins and may target the protein to lipid rafts. |
| Function | Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Increases cell growth inhibition activity of SSTR2 following heterodimerization. |
| Protein Name | Somatostatin Receptor Type 5Ss-5-RSs5-RSs5rSst5 |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Somatostatin Receptor Type 5 antibodyAnti-Ss-5-R antibodyAnti-Ss5-R antibodyAnti-Ss5r antibodyAnti-Sst5 antibodyAnti-SSTR5 antibody |
Information sourced from Uniprot.org
