• Immunohistochemistry analysis of paraffin-embedded human liver cancer using PRSS2 Rabbit monoclonal antibody (STJ11103006) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9. 0 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded rat pancreas using PRSS2 Rabbit monoclonal antibody (STJ11103006) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9. 0 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of extracts of various cell lines, using PRSS2 antibody (STJ11103006) at 1:5000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-PRSS2 antibody (1-100) [S6MR] (STJ11103006)

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STJ11103006

£212.50 - £501.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-PRSS2 (1-100) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: S6MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:2000-1:6000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PRSS2
Gene ID: 5645
Uniprot ID: TRY2_HUMAN
Immunogen Region: 1-100
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PRSS2 (P07478).
Immunogen Sequence: MNLLLILTFVAAAVAAPFDD DDKIVGGYICEENSVPYQVS LNSGYHFCGGSLISEQWVVS AGHCYKSRIQVRLGEHNIEV LEGNEQFINAAKIIRHPKYN
Tissue Specificity Expressed in Paneth cells, at the base of small intestinal crypts.
Post Translational Modifications Sulfated on tyrosine. Sulfation at Tyr-154 increases selectivity towards basic versus apolar residues at the P2' position of inhibitors that bind in a substrate-like fashion. Although the increase in selectivity is relatively small, it may facilitate digestion of a broader range of dietary proteins.
Function In the ileum, may be involved in defensin processing, including DEFA5.
Protein Name Trypsin-2
Anionic Trypsinogen
Serine Protease 2
Trypsin Ii
Database Links Reactome: R-HSA-1442490
Reactome: R-HSA-1462054
Reactome: R-HSA-1592389
Reactome: R-HSA-6798695
Reactome: R-HSA-6803157
Cellular Localisation Secreted
Extracellular Space
Alternative Antibody Names Anti-Trypsin-2 antibody
Anti-Anionic Trypsinogen antibody
Anti-Serine Protease 2 antibody
Anti-Trypsin Ii antibody
Anti-PRSS2 antibody
Anti-TRY2 antibody
Anti-TRYP2 antibody

Information sourced from Uniprot.org

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